MCH-1 antagonist 1 NLT 98%
SKU : MC503671
CAS Number : 1039825-68-7
Molecular Formula : C25H26N4O2 | Molecular Weight : 414.50
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
* The above information is for reference only.
* If the product has intellectual property rights, a license granted is must or contact us.
| Chemical Name | MCH-1 antagonist 1 |
|---|---|
| CAS Number | 1039825-68-7 |
| MDL Number | MFCD18633193 |
| Molecular Formula | C25H26N4O2 |
| Molecular Weight | 414.50 |
MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist with a Ki of 2.6 nM. MCH-1 antagonist 1 also inhibits CYP3A4 with an IC50 of 10 μM. IC50 & Target: Ki: 2.6 nM (MCH-1)[1]
IC50: 10 μM (CYP3A4)[1] In Vitro: MCH-1 antagonist 1 (Compound 1) also inhibits cytochrome P450 3A4 (CYP3A4) with an IC50 of 10 μM[1]. In Vivo: MCH-1 antagonist 1 is administered to male C57BL/6J DIO mice to assess their pharmacokinetic profile. Effect of MCH-1 antagonist 1 (dosed at 30 mg/kg, po) is measured on the body weight of DIO mice with the AUC0-6 h of 14760 h*ng/mL[1].
Related Products
© Copyright 2015-2024 Hangzhou MolCore BioPharmatech Co.,Ltd. All rights reserved.