SKU : MC503974
CAS Number : 104632-28-2
Molecular Formula : C10H17N3S | Molecular Weight : 211.33
Synonyms : (R)-Pramipexole;R-(+)-Pramipexole;KNS-760704
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Dexpramipexole |
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CAS Number | 104632-28-2 |
MDL Number | MFCD09033169 |
Molecular Formula | C10H17N3S |
Molecular Weight | 211.33 |
Synonyms | (R)-Pramipexole;R-(+)-Pramipexole;KNS-760704 |
Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. IC50 Value: Target: Dopamine Receptor Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity.
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