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104632-28-2 | Dexpramipexole

Dexpramipexole NLT 98%

SKU : MC503974

CAS Number : 104632-28-2

Molecular Formula : C10H17N3S | Molecular Weight : 211.33

Synonyms : (R)-Pramipexole;R-(+)-Pramipexole;KNS-760704

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Dexpramipexole
CAS Number 104632-28-2
MDL Number MFCD09033169
Molecular Formula C10H17N3S
Molecular Weight 211.33
Synonyms (R)-Pramipexole;R-(+)-Pramipexole;KNS-760704
Introduction of 104632-28-2 :

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. IC50 Value: Target: Dopamine Receptor Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity.

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