SKU : MC504608
CAS Number : 10592-13-9
Molecular Formula : C24H33ClN2O10 | Molecular Weight : 544.98
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Doxycycline (hydrochloride) |
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CAS Number | 10592-13-9 |
MDL Number | MFCD06200253 |
Molecular Formula | C24H33ClN2O10 |
Molecular Weight | 544.98 |
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor[1]. In Vitro: Doxycycline hydrochloride affects growth of glioma cells only under high concentrations[2].
Doxycycline hydrochloride decreases MT-CO1 protein content with concentrations of 1 µg/mL and higher in SVG cells[2].
In Vivo: Doxycycline hydrochloride (oral; 200 or 800 mg/kg/day; for 3 months) reduces active MMP-9 in untreated HT mice in a dose-dependent manner[1]
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