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1108-68-5 | Cinobufotalin

Cinobufotalin NLT 98%

SKU : MC506614

CAS Number : 1108-68-5

Molecular Formula : C26H34O7 | Molecular Weight : 458.54

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Cinobufotalin
CAS Number 1108-68-5
MDL Number MFCD00055946
Molecular Formula C26H34O7
Molecular Weight 458.54
Introduction of 1108-68-5 :

Cinobufotalin is a cardiotonic steroids or bufadienolides, is extracted from the skin secretions of the giant toads. Cinobufotalin has been used as a cardiotonic, diuretic and a hemostatic agent, Cinobufotalin is also a potential anti-lung cancer agent[1]. In Vitro: Cinobufotalin (0.1-10 µM; 72 hours; A549, H460 and HTB-58 human lung cancer cells) treatment induces cytotoxic effect against lung cancer cells[1]. In Vivo: Cinobufotalin (1-5 mg/kg; intraperitoneal injection; twice daily; for 1 weeks; male nude mice) treatment inhibits A549 lung cancer cell growth in vivo[1].

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