Pam3CSK4 NLT 98%
SKU : MC507052
CAS Number : 112208-00-1
Molecular Formula : C81H156N10O13S | Molecular Weight : 1510.23
Synonyms : Pam3Cys-Ser-(Lys)4
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Pam3CSK4 |
|---|---|
| CAS Number | 112208-00-1 |
| MDL Number | MFCD06801383 |
| Molecular Formula | C81H156N10O13S |
| Molecular Weight | 1510.23 |
| Synonyms | Pam3Cys-Ser-(Lys)4 |
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1]. In Vitro: Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1].
Pam3CSK4 (1 μg/mL) enhances the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils to Methicillin-resistant Staphylococcus aureus[2]. In Vivo: Pam3CSK4 (5 mg/kg; i.p.; once a day for 9 days) alters brain, spleen and liver weights in neonatal mice[3].
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