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1129669-05-1 | IM-12

IM-12 NLT 98%

SKU : MC507290

CAS Number : 1129669-05-1

Molecular Formula : C22H20FN3O2 | Molecular Weight : 377.41

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name IM-12
CAS Number 1129669-05-1
MDL Number MFCD20527313
Molecular Formula C22H20FN3O2
Molecular Weight 377.41
Introduction of 1129669-05-1 :

IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling. IC50 & Target: IC50: 53 nM (GSK-3β)[1] In Vitro: IM-12 inhibits GSK-3β in ReNcell VM cells, with I50 of 3.8 μM. IM-12 (3 μM) enhances the β-catenin amount, with no further effect at lower or higher concentration. IM-12 (3 μM) also attenuates the proliferation of ReNCell VM cells. IM-12 increases TCF-activity of ReNcell VM[1].

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