MTEP (hydrochloride) NLT 98%
SKU : MC509682
CAS Number : 1186195-60-7
Molecular Formula : C11H9ClN2S | Molecular Weight : 236.72
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | MTEP (hydrochloride) |
|---|---|
| CAS Number | 1186195-60-7 |
| MDL Number | MFCD08458895 |
| Molecular Formula | C11H9ClN2S |
| Molecular Weight | 236.72 |
Introduction of 1186195-60-7 :
MTEP hydrochloride is a potent, selective and non-competitive mGlu5 antagonist with an IC50 of 5 nM and a Ki of 16 nM[1]. MTEP hydrochloride produces antiparkinsonian-like effects[2]. IC50 & Target: IC50: 5 nM (mGluR5)[1]
Ki: 16 nM (mGluR5)[1] In Vivo: MTEP hydrochloride (3-5 mg/2 ml/kg; i.p.) inhibits the catalepsy induced (0.5 mg/kg/2 ml; i.p.) by this neuroleptic[2].
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