SKU : MC509712
CAS Number : 1186372-20-2
Molecular Formula : C21H14ClFN2O2 | Molecular Weight : 380.80
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | TMN355 |
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CAS Number | 1186372-20-2 |
MDL Number | MFCD19440965 |
Molecular Formula | C21H14ClFN2O2 |
Molecular Weight | 380.80 |
TMN355 is a potent chemical cyclophilin A inhibitor and reduces foam cell formation and cytokine secretion. TMN355 is used for atherosclerosis[1]. IC50 & Target: cyclophilin A[1] In Vitro: TMN 355 (0.5-10 μM; 3-9 hours) results in 75.9% reduction of cyclophilin A protein expression. And 1 μM TMN 355 inhibits cyclophilin A after 6 h of activation[1].
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