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1186372-20-2 | TMN355

TMN355 NLT 98%

SKU : MC509712

CAS Number : 1186372-20-2

Molecular Formula : C21H14ClFN2O2 | Molecular Weight : 380.80

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name TMN355
CAS Number 1186372-20-2
MDL Number MFCD19440965
Molecular Formula C21H14ClFN2O2
Molecular Weight 380.80
Introduction of 1186372-20-2 :

TMN355 is a potent chemical cyclophilin A inhibitor and reduces foam cell formation and cytokine secretion. TMN355 is used for atherosclerosis[1]. IC50 & Target: cyclophilin A[1] In Vitro: TMN 355 (0.5-10 μM; 3-9 hours) results in 75.9% reduction of cyclophilin A protein expression. And 1 μM TMN 355 inhibits cyclophilin A after 6 h of activation[1].

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