FR 167653 NLT 98%
SKU : MC528127
CAS Number : 158876-66-5
Molecular Formula : C24H20FN5O6S | Molecular Weight : 525.51
Synonyms : FR 167653 sulfate
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | FR 167653 |
|---|---|
| CAS Number | 158876-66-5 |
| MDL Number | MFCD00932388 |
| Molecular Formula | C24H20FN5O6S |
| Molecular Weight | 525.51 |
| Synonyms | FR 167653 sulfate |
FR 167653 (FR 167653 sulfate), an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 (FR 167653 sulfate) is effective in treating inflammation, relieving trauma and ischemia-reperfusion injury in vivo[1][2][3]. IC50 & Target: p38 MAPK[1] In Vivo: FR 167653 (FR 167653 sulfate) (32 mg/kg; i.h.; 24-48 hours) significantly decreases the extent of acute tubular necrosis[1].
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