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168135-77-1 | Fmoc-Tyr(malonyl-di-OtBu)-OH

Fmoc-Tyr(malonyl-di-OtBu)-OH 98% Min.

SKU : MC437614

CAS Number : 168135-77-1

Molecular Formula : C35H39NO9 | Molecular Weight : 617.69

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Purity 98% Min.
Storage -20 ± 5 ºC
*The above information is for reference only.
Chemical Name Fmoc-Tyr(malonyl-di-OtBu)-OH
CAS Number 168135-77-1
MDL Number MFCD00672344
Molecular Formula C35H39NO9
Molecular Weight 617.69
The phosphotyrosine-mimicking amino acid Fmoc-Tyr(malonyl-di-OtBu)-OH can be used as a building block for the synthesis of cell-permeable protein tyrosine phosphatase (PTP) inhibitors. The effect of a malonyl-tyrosine containing peptide on PTP 1B catalyzed insulin receptor dephosphorylation has been examined and it was shown that this peptide inhibited PTP 1B 20 times more potently than the corresponding phosphotyrosine containing peptide.

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