Boc-Asp(OBzl)-chloromethylketone NLT 98%
SKU : MC436370
CAS Number : 172702-58-8
Molecular Formula : C17H22ClNO5 | Molecular Weight : 355.81
Synonyms : Boc-Asp(OBzl)-CMK
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
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| Chemical Name | Boc-Asp(OBzl)-chloromethylketone |
|---|---|
| CAS Number | 172702-58-8 |
| MDL Number | MFCD00672491 |
| Molecular Formula | C17H22ClNO5 |
| Molecular Weight | 355.81 |
| Synonyms | Boc-Asp(OBzl)-CMK |
Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without affecting tumor necrosis factor processing.
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