Tel: +86 (0)571 8102-5280 Email: sales@molcore.com
198470-84-7 | Parecoxib

Parecoxib NLT 98%

SKU : MC537198

CAS Number : 198470-84-7

Molecular Formula : C19H18N2O4S | Molecular Weight : 370.42

Synonyms : SC 69124

Quote Request
Purity NLT 98%
Storage at 20ºC 2 years

* The above information is for reference only.

* If the product has intellectual property rights, a license granted is must or contact us.

Chemical Name Parecoxib
CAS Number 198470-84-7
MDL Number MFCD08141856
Molecular Formula C19H18N2O4S
Molecular Weight 370.42
Synonyms SC 69124
Introduction of 198470-84-7 :

Parecoxib is a potent and selective COX-2 inhibitor. IC50 value: Target: COX-2 in vitro: The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue [1]. in vivo: Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days [2]. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision [3].

Related Products