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200616-39-3 | Fmoc-Glu(2-phenylisopropyl ester)-OH

Fmoc-Glu(2-phenylisopropyl ester)-OH 98% Min.

SKU : MC437305

CAS Number : 200616-39-3

Molecular Formula : C29H29NO6 | Molecular Weight : 487.54

Synonyms : Fmoc-Glu(OPp)-OH;Fmoc-Glu(O-2-PhiPr)-OH

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Purity 98% Min.
Storage -20 ± 5 ºC
*The above information is for reference only.
Chemical Name Fmoc-Glu(2-phenylisopropyl ester)-OH
CAS Number 200616-39-3
MDL Number MFCD00672323
Molecular Formula C29H29NO6
Molecular Weight 487.54
Synonyms Fmoc-Glu(OPp)-OH;Fmoc-Glu(O-2-PhiPr)-OH
Glu-derivative for the selective modification of the γ-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.

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