Fmoc-Glu(2-phenylisopropyl ester)-OH NLT 98%
SKU : MC437305
CAS Number : 200616-39-3
Molecular Formula : C29H29NO6 | Molecular Weight : 487.54
Synonyms : Fmoc-Glu(OPp)-OH;Fmoc-Glu(O-2-PhiPr)-OH
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
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| Chemical Name | Fmoc-Glu(2-phenylisopropyl ester)-OH |
|---|---|
| CAS Number | 200616-39-3 |
| MDL Number | MFCD00672323 |
| Molecular Formula | C29H29NO6 |
| Molecular Weight | 487.54 |
| Synonyms | Fmoc-Glu(OPp)-OH;Fmoc-Glu(O-2-PhiPr)-OH |
Glu-derivative for the selective modification of the γ-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.
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