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220643-77-6 | p-MPPI (hydrochloride)

p-MPPI (hydrochloride) NLT 98%

SKU : MC541679

CAS Number : 220643-77-6

Molecular Formula : C25H28ClIN4O2 | Molecular Weight : 578.87

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name p-MPPI (hydrochloride)
CAS Number 220643-77-6
MDL Number MFCD00467897
Molecular Formula C25H28ClIN4O2
Molecular Weight 578.87
Introduction of 220643-77-6 :

p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist with high affinity for 5-HT1A receptors. p-MPPI hydrochloride can crosses the blood-brain barrier, and has clear antidepressant and anxiolytic-like effects[1][2]. In Vitro: p-MPPI hydrochloride has no agonist activity in both in vitro and in vivo tests of pre- and post-synaptic 5-HT1A receptor activity[1]. In Vivo: p-MPPI hydrochloride (0.5-4.5 mg/kg; i.p.) shows anxiolytic-like profile in the murine elevated plus-maze[2].

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