SKU : MC547770
CAS Number : 31008-19-2
Molecular Formula : C21H22O6 | Molecular Weight : 370.40
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Fargesin |
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CAS Number | 31008-19-2 |
MDL Number | MFCD07781423 |
Molecular Formula | C21H22O6 |
Molecular Weight | 370.40 |
Fargesin is a bioactive neolignan isolated from magnolia plants,with antihypertensive and anti-inflammatory effects[1][2][3]. In Vitro: Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB[3].
Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis[4].
In Vivo: Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release[1].
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