SKU : MC552641
CAS Number : 39011-92-2
Molecular Formula : C31H42O17 | Molecular Weight : 686.65
Synonyms : (8E)-Nuezhenide
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Specnuezhenide |
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CAS Number | 39011-92-2 |
MDL Number | MFCD20274720 |
Molecular Formula | C31H42O17 |
Molecular Weight | 686.65 |
Synonyms | (8E)-Nuezhenide |
Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA)[1]. In Vitro: Specnuezhenide (0.2-5.0 μg/mL) significantly decreases the mRNA expression of VEGFA induced by CoCl2 as a dose-dependent manner in ARPE-19 cells[2].
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