Custom Synthesis

At MolCore, we provide comprehensive custom synthesis services tailored to support pharmaceutical research, process development, and commercial manufacturing. Our expertise spans from milligram-scale synthesis for early-stage discovery to kilogram-scale deliveries for pilot and clinical phases. Whether you are developing a new chemical entity or need a specific intermediate, impurity, or metabolite, we offer flexible, confidential, and cost-effective solutions.

We routinely synthesize a wide variety of compounds, including:

• Drug-like small molecules and fragments
• Pharmaceutical intermediates, building blocks, and analogs
• Reference standards, impurities, and metabolites
• Process-related contaminants and degradation products
• Specialty and fine chemicals for research or industrial use

Our team is particularly skilled in the design and synthesis of API intermediates and high-complexity molecules, supporting both medicinal chemistry and process chemistry demands. We are also capable of replicating published routes or developing de novo synthetic strategies for novel compounds.

Our end-to-end services include:

• Route design and retrosynthetic analysis
• Literature synthesis and known compound reproduction
• Multi-step synthesis and complex heterocycle construction
• Chiral compound synthesis and asymmetric transformations
• Process development, optimization, and scale-up
• Comprehensive analytical characterization (NMR, LC-MS, HPLC, GC, etc.)

With an international network of partners and robust supply chain resources, we ensure efficient raw material sourcing, cost control, and global delivery. All projects are conducted under strict confidentiality agreements, with full documentation and analytical data provided upon completion.

We pride ourselves on rapid response — most inquiries are answered within 2 to 24 hours. Our customer-centric approach, scientific rigor, and flexibility make MolCore a trusted partner for your custom synthesis needs.