Tilapertin NLT 98%
SKU : MC500236
CAS Number : 1000690-85-6
Molecular Formula : C20H21F3N2O2 | Molecular Weight : 378.39
Synonyms : AMG747
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Tilapertin |
|---|---|
| CAS Number | 1000690-85-6 |
| Molecular Formula | C20H21F3N2O2 |
| Molecular Weight | 378.39 |
| Synonyms | AMG747 |
Introduction of 1000690-85-6 :
Tilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1). IC50 & Target: GlyT1[1] In Vivo: Tilapertin is a nanomolar potent, orally bioavailable and selective GlyT1 inhibitor. Oral administration of Tilapertin dose-dependently increases cerebrospinal fluid (CSF) glycine concentration in rats[1].
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