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100299-08-9 | Pemirolast (potassium)

Pemirolast (potassium) NLT 98%

SKU : MC500526

CAS Number : 100299-08-9

Molecular Formula : C10H9KN6O2 | Molecular Weight : 284.32

Synonyms : TWT-8152;BMY 26517

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Pemirolast (potassium)
CAS Number 100299-08-9
MDL Number MFCD22575284
Molecular Formula C10H9KN6O2
Molecular Weight 284.32
Synonyms TWT-8152;BMY 26517
Introduction of 100299-08-9 :

Pemirolast potassium (TWT-8152) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. Target: Histamine H1 Receptor Pemirolast potassium (TWT-8152) is a new oral, nonbronchodilator antiallergy medication that is being evaluated for the therapy of asthma [1]. Pemirolast potassium (TWT-8152) inhibits chemical mediator release from tissue mast cells and is also shown to inhibit the release of peptides including substance P, Pemirolast potassium (TWT-8152) reduces kaolin intake by inhibition of substance P release in rats [2]. Pemirolast potassium (TWT-8152) potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats [3]. Pemirolast potassium (TWT-8152) potassium is used for the treatment of allergic conjunctivitis and prophylaxis for pulmonary hypersensitivity reactions to drugs such as paclitaxel [4].

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