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10048-13-2 | Sterigmatocystine

Sterigmatocystine NLT 98%

SKU : MC500719

CAS Number : 10048-13-2

Molecular Formula : C18H12O6 | Molecular Weight : 324.28

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Sterigmatocystine
CAS Number 10048-13-2
MDL Number MFCD00005084
Molecular Formula C18H12O6
Molecular Weight 324.28
Introduction of 10048-13-2 :

Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor[1][2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals[3]. In Vitro: Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, which contributes to the induction of G2 arrest in GES-1 cells[4]. In Vivo: Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) inhibits p21WAF1/CIP1[3].

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