Sterigmatocystine NLT 98%
SKU : MC500719
CAS Number : 10048-13-2
Molecular Formula : C18H12O6 | Molecular Weight : 324.28
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Sterigmatocystine |
|---|---|
| CAS Number | 10048-13-2 |
| MDL Number | MFCD00005084 |
| Molecular Formula | C18H12O6 |
| Molecular Weight | 324.28 |
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor[1][2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals[3]. In Vitro: Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, which contributes to the induction of G2 arrest in GES-1 cells[4]. In Vivo: Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) inhibits p21WAF1/CIP1[3].
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