Tel: +86 (0)571 8102-5280 Email: sales@molcore.com
1005264-47-0 | MX69

MX69 NLT 98%

SKU : MC500824

CAS Number : 1005264-47-0

Molecular Formula : C27H26N2O4S | Molecular Weight : 474.57

Quote Request
Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.
Chemical Name MX69
CAS Number 1005264-47-0
Molecular Formula C27H26N2O4S
Molecular Weight 474.57
Introduction of 1005264-47-0 :

MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. In Vitro: MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1]. In Vivo: MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].

Related Products