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1005549-94-9 | Taprenepag isopropyl

Taprenepag isopropyl NLT 98%

SKU : MC500857

CAS Number : 1005549-94-9

Molecular Formula : C27H28N4O5S | Molecular Weight : 520.60

Synonyms : PF-04217329

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Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.
Chemical Name Taprenepag isopropyl
CAS Number 1005549-94-9
Molecular Formula C27H28N4O5S
Molecular Weight 520.60
Synonyms PF-04217329
Introduction of 1005549-94-9 :

Taprenepag isopropyl is a highly selective EP2 receptor agonist. IC50 & Target: EP2 receptor[1] In Vivo: Taprenepag isopropyl is a highly selective EP2 receptor agonist. Intraocular pressure (IOP) in the left, vehicle-dosed eye typically remains within the normal range. In the right (Taprenepag isopropyl-dosed) eye, IOP is reduced in all dose groups. In the high-dose group, IOP is reduced to the extent that it cannot be measured (<4mm Hg) on Days 22 and 29. There are no clinical signs or changes in body weight observed with any dose of Taprenepag isopropyl administration, and no ocular findings occur for animals in the low-dose group (0.75 mg/day)[1].

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