![1005883-72-6 | Ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate](https://stcdn.molcore.com/molcore/structure/MC500889.png "1005883-72-6 | Ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate")
Ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate
NLT 98%
SKU : MC500889
CAS Number : 1005883-72-6
Molecular Formula : C20H20N4O3 | Molecular Weight : 364.40
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate |
|---|---|
| CAS Number | 1005883-72-6 |
| Molecular Formula | C20H20N4O3 |
| Molecular Weight | 364.40 |
Introduction of 1005883-72-6 :
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1]. IC50 & Target: IC50: ~0.2 µM (mAQP7), ~0.7 µM (mAQP3), ~1.1 µM (mAQP9)[1] In Vitro: Z433927330 inhibits glycerol permeability, with an IC50 of ~0.6 µM[1].
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