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1006028-37-0 | NF546

NF546 NLT 98%

SKU : MC500902

CAS Number : 1006028-37-0

Molecular Formula : C47H44N6Na4O17P4 | Molecular Weight : 1180.74

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Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.
Chemical Name NF546
CAS Number 1006028-37-0
Molecular Formula C47H44N6Na4O17P4
Molecular Weight 1180.74
Introduction of 1006028-37-0 :

NF546 is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 stimulates release of interleukin-8 from human monocyte-derived dendritic cells[1]. IC50 & Target: pEC50: 6.27 (P2Y11)[1] In Vitro: NF546 is relatively selective for P2Y11 over P2Y1, P2Y2, P2Y4, P2Y6, P2Y12, P2X1, P2X2, and P2X2-X3. NF546 (100 μM; 24 hours) is equi-efficacious in stimulating TSP-1 release and inhibiting the LPS-induced release of IL-12p70 in human monocyte-derived dendritic cells[1].

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