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1007392-69-9 | ACT 178882

ACT 178882 NLT 98%

Product Number : MC501073

CAS Number : 1007392-69-9

Molecular Formula : C33H38Cl3N3O4 | Molecular Weight : 647.03

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Purity NLT 98%
Storage at 20ºC 2 years
MolCore specializes in manufacturing high-purity CAS No.1007392-69-9, ACT 178882 with the molecular formula C33H38Cl3N3O4 and molecular weight 647.03 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems.

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Chemical Name ACT 178882
CAS Number 1007392-69-9
Molecular Formula C33H38Cl3N3O4
Molecular Weight 647.03
Introduction of 1007392-69-9 :

ACT 178882 is a new Renin inhibitor with an IC50 of 1.4 nM. IC50 & Target: IC50: 1.4 nM (Renin)[1] In Vitro: The median time to Cmax (tmax) for ACT 178882 is prolonged from 3.5 to 5.0 h by diltiazem whereas its apparent terminal half-life (t½) is unaffected by diltiazem, 22.9 and 24.2 h for treatments A and B, respectively. Using treatment A as reference, the geometric mean ratio (90% CI) is 1.62 (1.36 to 1.94) for Cmax and 2.02 (1.75 to 2.34) for AUC, indicating a significant interaction between ACT 178882 and diltiazem[2].