Smurf1-IN-A01 NLT 98%
SKU : MC501114
CAS Number : 1007647-73-5
Molecular Formula : C22H20ClF3N4O3S | Molecular Weight : 512.93
Synonyms : A01;1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-[4-(5-methyl-1H-pyrazol-1-yl)benzoyl]piperazine
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Smurf1-IN-A01 |
|---|---|
| CAS Number | 1007647-73-5 |
| Molecular Formula | C22H20ClF3N4O3S |
| Molecular Weight | 512.93 |
| Synonyms | A01;1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-[4-(5-methyl-1H-pyrazol-1-yl)benzoyl]piperazine |
Introduction of 1007647-73-5 :
Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation[1]. IC50 & Target: Kd: 3.664 nM (Smurf1)[1]
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