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1007647-73-5 | Smurf1-IN-A01

Smurf1-IN-A01 NLT 98%

SKU : MC501114

CAS Number : 1007647-73-5

Molecular Formula : C22H20ClF3N4O3S | Molecular Weight : 512.93

Synonyms : A01;1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-[4-(5-methyl-1H-pyrazol-1-yl)benzoyl]piperazine

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Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.
Chemical Name Smurf1-IN-A01
CAS Number 1007647-73-5
Molecular Formula C22H20ClF3N4O3S
Molecular Weight 512.93
Synonyms A01;1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-[4-(5-methyl-1H-pyrazol-1-yl)benzoyl]piperazine
Introduction of 1007647-73-5 :

Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation[1]. IC50 & Target: Kd: 3.664 nM (Smurf1)[1]

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