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10083-24-6 | Piceatannol

Piceatannol NLT 98%

SKU : MC501204

CAS Number : 10083-24-6

Molecular Formula : C14H12O4 | Molecular Weight : 244.24

Synonyms : Astringenin;trans-Piceatannol

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Piceatannol
CAS Number 10083-24-6
MDL Number MFCD00221715
Molecular Formula C14H12O4
Molecular Weight 244.24
Synonyms Astringenin;trans-Piceatannol
Introduction of 10083-24-6 :

Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1]

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