SKU : MC501256
CAS Number : 1008763-54-9
Molecular Formula : C21H32ClN3O3 | Molecular Weight : 409.95
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | D-3263 (hydrochloride) |
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CAS Number | 1008763-54-9 |
MDL Number | MFCD22665741 |
Molecular Formula | C21H32ClN3O3 |
Molecular Weight | 409.95 |
D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. In Vitro: D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].
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