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1009104-85-1 | SIS3 (free base)

SIS3 (free base) NLT 98%

SKU : MC501303

CAS Number : 1009104-85-1

Molecular Formula : C28H27N3O3 | Molecular Weight : 453.53

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Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.
Chemical Name SIS3 (free base)
CAS Number 1009104-85-1
Molecular Formula C28H27N3O3
Molecular Weight 453.53
Introduction of 1009104-85-1 :

SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1[1]. IC50 & Target: Smad3, ALK-5[1] In Vitro: SIS3 free base attenuates the TGF-beta1-induced phosphorylation of Smad3 and interaction of Smad3 with Smad4[1].

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