Desethyl KBT-3022 NLT 98%
SKU : MC501483
CAS Number : 101001-72-3
Molecular Formula : C23H20N2O4S | Molecular Weight : 420.48
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Desethyl KBT-3022 |
|---|---|
| CAS Number | 101001-72-3 |
| Molecular Formula | C23H20N2O4S |
| Molecular Weight | 420.48 |
Desethyl KBT-3022 is the main active metabolite of the new antiplatelet agent, KBT-3022. In Vitro: Pretreatment with desethyl KBT-3022 0.1, 0.3 and 1 mg/kg, i.v. prolongs the time required to achieve thrombotic occlusion in the femoral artery and inhibits collagen-induced platelet aggregation in whole blood ex vivo, each in a dose-dependent manner. Desethyl KBT-3022 inhibits the thrombin-induced aggregation of washed platelets in a concentration-dependent manner 1–40 μM[1].
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