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Introduction of 1010073-75-2 :
CCX354 is an antagonist of CCR1, with anti-inflammatory activity. IC50 & Target: CCR1In Vitro: CCX354 shows potent activities in the chemotaxis assay, with IC50 < 100 nM. In Vivo: In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties.