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Introduction of 1011531-27-3 :
AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively. IC50 & Target: EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)