1020412-43-4

Gardiquimod NLT 98%

Name: Gardiquimod
Brand: Molcore
SKU: MC502415
Rating: 96 (40 reviews)

Product Number : MC502415

CAS Number : 1020412-43-4

Molecular Formula : C17H23N5O | Molecular Weight : 313.40

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Specifications
Product Details

Purity	NLT 98%
Storage	at 20ºC 2 years
MolCore specializes in manufacturing high-purity CAS No.1020412-43-4, Gardiquimod with the molecular formula C17H23N5O and molecular weight 313.40 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems.

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Chemical Name	Gardiquimod
CAS Number	1020412-43-4
Molecular Formula	C17H23N5O
Molecular Weight	313.40

Introduction of 1020412-43-4 :

Gardiquimod, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod specifically activates TLR7 when used at concentrations below 10 μM^[1]^[2]. IC50 & Target: TLR7, HIV-1 reverse transcriptase^[1] In Vitro: Gardiquimod (6-60 μM ) significantly inhibits cDNA synthesis by HIV-1 reverse transcriptase^[1]. In Vivo: Dendritic cells (DCs) in combination with Gardiquimod (1 mg/kg per mouse; i.p.; daily for 7 days) improves the anti-tumor effects of NK cells^[2].