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102115-79-7 | Pseudoprotodioscin

Pseudoprotodioscin NLT 98%

SKU : MC502480

CAS Number : 102115-79-7

Molecular Formula : C51H82O21 | Molecular Weight : 1031.18

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Pseudoprotodioscin
CAS Number 102115-79-7
MDL Number MFCD04039839
Molecular Formula C51H82O21
Molecular Weight 1031.18
Introduction of 102115-79-7 :

Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1]. In Vitro: In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels[1].

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