Jasplakinolide NLT 98%
Product Number : MC502687
CAS Number : 102396-24-7
Molecular Formula : C36H45BrN4O6 | Molecular Weight : 709.67
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.102396-24-7, Jasplakinolide with the molecular formula C36H45BrN4O6 and molecular weight 709.67 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | Jasplakinolide |
|---|---|
| CAS Number | 102396-24-7 |
| MDL Number | MFCD00467745 |
| Molecular Formula | C36H45BrN4O6 |
| Molecular Weight | 709.67 |
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity[1][2]. In Vitro: Jasplakinolide has an IC50 of 35 nM for the antiproliferative effect of jasplakinolide on PC3 prostate carcinoma cells[2].
Jasplakinolide (10 μM; for 2 hours) generates binucleated cells when applied during mitosis. Jasplakinolide induces the formation of F-actin-containing apical extensions in Toxoplasma gondii tachyzoites[2].
Jasplakinolide (1 mM; for 60 min) induces the formation of actin-containing apical extensions in isolated Toxoplasma gondii tachyzoites fixed[2].
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