BAY 60-2770 NLT 98%
SKU : MC502935
CAS Number : 1027642-43-8
Molecular Formula : C35H33F4NO5 | Molecular Weight : 623.63
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | BAY 60-2770 |
|---|---|
| CAS Number | 1027642-43-8 |
| Molecular Formula | C35H33F4NO5 |
| Molecular Weight | 623.63 |
BAY 60-2770 is a potent, selective, and orally active soluble guanylyl cyclase (sGC) activator. BAY 60-2770 increases the activity of sGC in a nitric oxide-independent manner. BAY 60-2770 shows antifibrotic effect[1][2]. In Vivo: BAY 60-2770 (0.1-0.3 mg/Kg; p.o.) attenuates liver fibrosis in two rat models[1].
BAY 60-2770 (1 mg/kg; p.o.; daily from the 10th to the 12th week) results in amelioration of bladder dysfunction in high-fat obese mice[2].
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