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Introduction of 1028089-05-5 :
Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.