103476-89-7

Leupeptin (hemisulfate) NLT 98%

Name: Leupeptin (hemisulfate)
Brand: Molcore
SKU: MC503419
Rating: 96 (42 reviews)

Product Number : MC503419

CAS Number : 103476-89-7

Molecular Formula : C20H38N6O4 | Molecular Weight : 426.55

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Specifications
Product Details

Purity	NLT 98%
Storage	at 20ºC 2 years
MolCore specializes in manufacturing high-purity CAS No.103476-89-7, Leupeptin (hemisulfate) with the molecular formula C20H38N6O4 and molecular weight 426.55 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems.

* The above information is for reference only.

Chemical Name	Leupeptin (hemisulfate)
CAS Number	103476-89-7
MDL Number	MFCD00081028
Molecular Formula	C20H38N6O4
Molecular Weight	426.55

Introduction of 103476-89-7 :

Leupeptin hemisulfate is a membrane-permeable thiolprotease inhibitor that inhibits Cathepsin B, Cathepsin H and Cathepsin L, and also impairs amphisome-lysosome fusion^[1]. Leupeptin hemisulfate also exhibits anti-inflammatory effect^[2]. IC50 & Target: Cathepsin^[1] In Vivo: Leupeptin (0-36 mg/kg; intraperitoneal injection; for 4 hours; C57BL/6NCrl male mice) is well tolerated by the animals and produces a strong, dose-dependent increase in LC3b-II in both the total tissue extracts and the lysosome and autophagosome-enriched pellet fraction^[2].