SKU : MC506085
CAS Number : 109683-61-6
Molecular Formula : C22H31N3O5S | Molecular Weight : 449.56
Synonyms : FPL 63547
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Utibapril |
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CAS Number | 109683-61-6 |
MDL Number | MFCD00865862 |
Molecular Formula | C22H31N3O5S |
Molecular Weight | 449.56 |
Synonyms | FPL 63547 |
Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities. In Vivo: Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril[1]. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts[2].
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