SKU : MC506251
CAS Number : 11024-24-1
Molecular Formula : C56H92O29 | Molecular Weight : 1229.31
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Digitonin |
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CAS Number | 11024-24-1 |
MDL Number | MFCD00077729 |
Molecular Formula | C56H92O29 |
Molecular Weight | 1229.31 |
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth. In Vitro: Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can increase cisplatin accumulation and reduce tumour growth in vitro[1]. In Vivo: In the liver parenchyma the concentrations are of the same magnitude. Measured with the 133Xe-clearance technique, Digitonin does not alter the tumor blood flow. Digitonin enhances the tumor-growth retarding effect of CBDCA given intra-aterially at 5 mg/kg but not at 25 mg/kg[1].
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