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110588-57-3 | Saperconazole

Saperconazole NLT 98%

SKU : MC506563

CAS Number : 110588-57-3

Molecular Formula : C35H38F2N8O4 | Molecular Weight : 672.72

Synonyms : R66905

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Saperconazole
CAS Number 110588-57-3
MDL Number MFCD00872615
Molecular Formula C35H38F2N8O4
Molecular Weight 672.72
Synonyms R66905
Introduction of 110588-57-3 :

Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L. IC50 & Target: MIC90: 0.19 mg/L[1] In Vitro: The antifungal activity of Saperconazole is complete at 1 μg/mL for all but one strain of A. niger. Eighty percent of all strains show complete absence of growth at 0.1 μg/mL (85% for A. fumigatus), and this result persists during 14 days of the test[2]. In Vivo: All control pigeons infect with A. fumigatus die within 2 to 5 days. They have necrotic foci in the lungs, air sacs, liver, spleen, and kidneys. These organs are highly positive by histology and oncultures. Saperconazole administered at 2.5 mg/kg is not active, but when it is given at 5 or 10 mg/kg, 92 or 100%, respectively, survive and organ cultures are negative. No drug-related side effects are observed in the pigeons[2].

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