SKU : MC506563
CAS Number : 110588-57-3
Molecular Formula : C35H38F2N8O4 | Molecular Weight : 672.72
Synonyms : R66905
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Saperconazole |
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CAS Number | 110588-57-3 |
MDL Number | MFCD00872615 |
Molecular Formula | C35H38F2N8O4 |
Molecular Weight | 672.72 |
Synonyms | R66905 |
Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L. IC50 & Target: MIC90: 0.19 mg/L[1] In Vitro: The antifungal activity of Saperconazole is complete at 1 μg/mL for all but one strain of A. niger. Eighty percent of all strains show complete absence of growth at 0.1 μg/mL (85% for A. fumigatus), and this result persists during 14 days of the test[2]. In Vivo: All control pigeons infect with A. fumigatus die within 2 to 5 days. They have necrotic foci in the lungs, air sacs, liver, spleen, and kidneys. These organs are highly positive by histology and oncultures. Saperconazole administered at 2.5 mg/kg is not active, but when it is given at 5 or 10 mg/kg, 92 or 100%, respectively, survive and organ cultures are negative. No drug-related side effects are observed in the pigeons[2].
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