1118460-77-7

UCPH-101 NLT 98%

Name: UCPH-101
Brand: Molcore
SKU: MC506912
Rating: 97 (26 reviews)

SKU : MC506912

CAS Number : 1118460-77-7

Molecular Formula : C27H22N2O3 | Molecular Weight : 422.48

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Purity	NLT 98%
Storage	at 20ºC 2 years

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Chemical Name	UCPH-101
CAS Number	1118460-77-7
MDL Number	MFCD12913298
Molecular Formula	C27H22N2O3
Molecular Weight	422.48

Introduction of 1118460-77-7 :

UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC₅₀ of 0.66 μM. IC50 & Target: IC50: 0.66 μM (EAAT1)^[1] In Vitro: UCPH-101 and UCPH-102 inhibit EAAT1 anion currents in a concentration-dependent manner, with K_D values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. A small but significant decrease in the total expression levels of both HA-EAAT1 and HA-GLAST is observed in cells preincubated with 100 μM UCPH-101 (p=0.048)^[1].

1118460-77-7

UCPH-101 NLT 98%

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