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112732-17-9 | Enrofloxacin (hydrochloride)

Enrofloxacin (hydrochloride) NLT 98%

SKU : MC507211

CAS Number : 112732-17-9

Molecular Formula : C19H23ClFN3O3 | Molecular Weight : 395.86

Synonyms : BAY Vp 2674 (hydrochloride);PD160788 (hydrochloride)

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Enrofloxacin (hydrochloride)
CAS Number 112732-17-9
MDL Number MFCD01861684
Molecular Formula C19H23ClFN3O3
Molecular Weight 395.86
Synonyms BAY Vp 2674 (hydrochloride);PD160788 (hydrochloride)
Introduction of 112732-17-9 :

Enrofloxacin hydrochloride (BAY Vp 2674 hydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. IC50 & Target: MIC90: 0.312 μg/mL ( Mycoplasma bovis)[1] In Vitro: Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The antibiotic susceptibility profiles of the Hungarian strains are consistent within the tested group of fluoroquinolones. Three isolates (MYC44, MYC45 and MYC46) have high MIC values (≥10 μg/mL) to Enrofloxacin, while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0.312 or 0.625 μg/mL[1]. In Vivo: Mice (n=80) undergo transient middle cerebral artery occlusion (MCAo) with reperfusion after 60 minutes. After MCAo, animals are randomly assigned to receive either a daily preventive medication (n=26, Enrofloxacin) starting at the day of MCAo or a therapeutic medication (n=25; Enrofloxacin) after diagnosis of lung infection. Standard treatment started immediately after the appearance of clinical signs (general health score>6) usually between day 4 and 6 after stroke. Both, preventive and standard antibiotic treatment using Enrofloxacin improve survival in a similar way compared with placebo treatment[2].

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