SKU : MC507961
CAS Number : 114870-03-0
Molecular Formula : C31H43N3Na10O49S8 | Molecular Weight : 1728.08
Synonyms : Fondaparin sodium;SR-90107A
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Fondaparinux (sodium) |
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CAS Number | 114870-03-0 |
MDL Number | MFCD06794972 |
Molecular Formula | C31H43N3Na10O49S8 |
Molecular Weight | 1728.08 |
Synonyms | Fondaparin sodium;SR-90107A |
Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor. IC50 & Target: Factor Xa[1] In Vitro: Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50 values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs)[2]. In Vivo: Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation[1].
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