Fumonisin B1 NLT 98%
SKU : MC508714
CAS Number : 116355-83-0
Molecular Formula : C34H59NO15 | Molecular Weight : 721.83
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Fumonisin B1 |
|---|---|
| CAS Number | 116355-83-0 |
| MDL Number | MFCD00133349 |
| Molecular Formula | C34H59NO15 |
| Molecular Weight | 721.83 |
Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[1][2]. IC50 & Target: Sphingosine N-acyltransferase[2] In Vitro: Fumonisin B1 alters the gene expression and signal transduction pathways in monkey kidney cells[3].
Fumonisin B1 increases the initial disruption of sphingolipid metabolism and the accumulation of sphinganine in LLC-PK1 kidney cells, causes DNA damage of apoptotic type in rat astrocytes[3].
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