JZL195 NLT 98%
Product Number : MC511712
CAS Number : 1210004-12-8
Molecular Formula : C24H23N3O5 | Molecular Weight : 433.46
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.1210004-12-8, JZL195 with the molecular formula C24H23N3O5 and molecular weight 433.46 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | JZL195 |
|---|---|
| CAS Number | 1210004-12-8 |
| MDL Number | MFCD18382122 |
| Molecular Formula | C24H23N3O5 |
| Molecular Weight | 433.46 |
JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively[1]. IC50 & Target: IC50: 2 nM (FAAH), 4 nM (MAGL)[1] In Vitro: JZL195 produces near-complete blockade of FP-Rh labeling of both mouse brain FAAH and MAGL at concentrations as low as 100 nM (IC50 values of 13 and 19 nM, respectively)[1].
JZL195 inhibits rat and human FAAH and MAGL enzymes with IC50 values in the range of ≈10-100 nM based on competitive ABPP assays[1]. In Vivo: JZL195 (20 mg/kg; i.p.) produces an antinociceptive response in the tail immersion assay[1].
© Copyright 2015-2025 Hangzhou MolCore BioPharmatech Co.,Ltd. All rights reserved.