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1253452-78-6 | KS176

KS176 NLT 98%

SKU : MC514470

CAS Number : 1253452-78-6

Molecular Formula : C22H19N3O5 | Molecular Weight : 405.40

Synonyms : N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide

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Purity NLT 98%
Boiling Point 510.1±50.0 ºC(Predicted)
Storage at 20ºC 2 years

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Chemical Name KS176
CAS Number 1253452-78-6
MDL Number MFCD22666402
Molecular Formula C22H19N3O5
Molecular Weight 405.40
Synonyms N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide
Introduction of 1253452-78-6 :

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1. IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay). Target: BCRP The more detailed information please refer to Compound 9 in the reference.

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