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136164-66-4 | E3330

E3330 NLT 98%

SKU : MC519797

CAS Number : 136164-66-4

Molecular Formula : C21H30O6 | Molecular Weight : 378.46

Synonyms : APX-3330

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name E3330
CAS Number 136164-66-4
MDL Number MFCD00901331
Molecular Formula C21H30O6
Molecular Weight 378.46
Synonyms APX-3330
Introduction of 136164-66-4 :

E3330 (APX-3330) is a direct, orally active AP endonuclease 1 (APE1; also known as REF-1) inhibitor, which suppresses NF-κB DNA-binding activity. E3330 (APX-3330) blocks TNF-α-induced activation of IL-8 production in liver cancer cell lines. E3330 (APX-3330) shows anticancer properties, such as inhibition of cancer cell growth and migration[1-4]. IC50 & Target: DNA Synthesis, APE1[1-4]

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