SKU : MC519797
CAS Number : 136164-66-4
Molecular Formula : C21H30O6 | Molecular Weight : 378.46
Synonyms : APX-3330
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | E3330 |
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CAS Number | 136164-66-4 |
MDL Number | MFCD00901331 |
Molecular Formula | C21H30O6 |
Molecular Weight | 378.46 |
Synonyms | APX-3330 |
E3330 (APX-3330) is a direct, orally active AP endonuclease 1 (APE1; also known as REF-1) inhibitor, which suppresses NF-κB DNA-binding activity. E3330 (APX-3330) blocks TNF-α-induced activation of IL-8 production in liver cancer cell lines. E3330 (APX-3330) shows anticancer properties, such as inhibition of cancer cell growth and migration[1-4]. IC50 & Target: DNA Synthesis, APE1[1-4]
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