A 1070722 NLT 98%
SKU : MC520959
CAS Number : 1384424-80-9
Molecular Formula : C17H13F3N4O2 | Molecular Weight : 362.31
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | A 1070722 |
|---|---|
| CAS Number | 1384424-80-9 |
| MDL Number | MFCD22580422 |
| Molecular Formula | C17H13F3N4O2 |
| Molecular Weight | 362.31 |
Introduction of 1384424-80-9 :
A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain[1]. IC50 & Target: Ki: 0.6 nM (GSK-3)[1]
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