Anakinra NLT 98%
Product Number : MC523420
CAS Number : 143090-92-0
Molecular Formula : C20H23N5O7S2 | Molecular Weight : 509.56
Synonyms : Raleukin;AMG-719
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.143090-92-0, Anakinra with the molecular formula C20H23N5O7S2 and molecular weight 509.56 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
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| Chemical Name | Anakinra |
|---|---|
| CAS Number | 143090-92-0 |
| MDL Number | MFCD00912203 |
| Molecular Formula | C20H23N5O7S2 |
| Molecular Weight | 509.56 |
| Synonyms | Raleukin;AMG-719 |
Anakinra (Raleukin) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects[1][2]. IC50 & Target: IL-1R[1]. In Vivo: Combined etanercept (5 mg/kg, ip) and Anakinra (100 mg/kg, I.P. daily for 7 days) substantially improves marginal mass human islet engraftment in immunodeficient mice[2].
Anakinra enhances tumor growth inhibition in mice receiving peptide vaccination and β-(1-3),(1-6)-D-glucan[3].
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